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KMID : 1102220200390020121
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Kidney Research and Clinical Practice
2020 Volume.39 No. 2 p.121 ~ p.135
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The KNOW-CKD Study: What we have learned about chronic kidney diseases
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Oh Kook-Hwan
Kang Min-Jung
Kang Eun-Jeong
Ryu Hyun-Jin
Han Seung-Hyeok
Yoo Tae-Hyun
Kim Soo-Wan
Chae Dong-Wan
Lee Kyu-Beck
Park Sue-K.
Kim Yeong-Hoon
Ahn Curie
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Abstract
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As the nation’s largest chronic kidney disease (CKD) cohort, the KoreaN Cohort Study for Outcomes in Patients With Chronic Kidney Disease (KNOW-CKD) was established to investigate the clinical course, risk factors for progression, and adverse outcomes of CKD. From 2011 to 2016, the KNOW-CKD recruited 2,238 adult patients with CKD from stage G1 to G5 who were not receiving renal replacement therapy from nine tertiary care hospitals throughout Korea. As of 2019, the KNOW-CKD has published more than 50 articles in the areas of socio-economics, nutrition, quality of life, health-related habits, CKD progression, cardiovascular comorbidity and outcome, anemia, mineral bone disease, biomarker discovery, and international and inter-ethnic comparisons. The KNOW-CKD will eventually offer a prediction model for long-term consequences of CKD, such as the occurrences of end-stage renal disease, cardiovascular disease, and death, thereby enabling the identification and treatment of at-risk populations that require extra medical attention.
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KEYWORD
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Chronic kidney disease, Cohort studies, Korea, Outcome
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